Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6794
Gene Symbol: STK11
STK11
0.100 CausalMutation phenotype CLINVAR
Entrez Id: 4295
Gene Symbol: MLN
MLN
0.020 AlteredExpression phenotype BEFREE However, the GD score and serum GAS, CCK, and MTL levels in the acute LF group were not statistically different, when compared with those in the subacute LF group, acute-on-chronic LF group and chronic LF group.LF plays a key role in the development of GD, and may be the main cause of obvious gastrointestinal symptoms, such as abdominal distension, nausea, vomiting and anorexia, in LF patients. 30508896 2018
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
0.020 AlteredExpression phenotype BEFREE <b>Methods</b> We compared serum levels of GDF15 and IGFBP7 at 12 and 24 weeks' gestation in women hospitalized for HG, and two control groups, women with nausea and vomiting of pregnancy (NVP), and women with no NVP. 31000883 2019
Entrez Id: 3490
Gene Symbol: IGFBP7
IGFBP7
0.020 AlteredExpression phenotype BEFREE <b>Methods</b> We compared serum levels of GDF15 and IGFBP7 at 12 and 24 weeks' gestation in women hospitalized for HG, and two control groups, women with nausea and vomiting of pregnancy (NVP), and women with no NVP. 31000883 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO
0.010 AlteredExpression phenotype BEFREE The levels of TNF-α, endotoxin, serum IL-1, IL-10, IL-15, IL-18 and intercellular adhesion molecule-1 (ICAM-1), myeloperoxidase (MPO) activity, incidence of nausea and vomiting, pulmonary histopathological changes, prognosis, and rehabilitation (time in bed, hospital stay and lung function) were compared between the two groups. 30186471 2018
Entrez Id: 952
Gene Symbol: CD38
CD38
0.010 AlteredExpression phenotype BEFREE The secondary outcomes hypotension, time for sensory block to recede to the level of T10, and the combined outcome of nausea and vomiting, did not differ significantly between the interventions. 29330854 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
0.010 AlteredExpression phenotype BEFREE Time to get out of bed, first bowel movement time and the average time of hospitalisation in group A was lower than group D (p less than 0.05), postoperative leukocyte level as well as the occurrence rate of nausea and vomiting, ankylenteron and pelvic adhesion was decreased in group A compared to group D (p less than 0.05), but the postoperative albumin and total protein level was higher than group D (p less than 0.05). 29254317 2018
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
0.010 AlteredExpression phenotype BEFREE In contrast, activation of ABCC1 using thiethylperazine (a drug approved by the FDA to relieve nausea and vomiting) markedly reduced Aβ load in a mouse model of AD expressing ABCC1 but not in such mice lacking ABCC1. 21881209 2011
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.110 Biomarker phenotype HPO
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.110 Biomarker phenotype BEFREE There was no difference in the sensitivity of the thenar and peri-incisional region after 6 and 24 hours; in the number of patients requiring supplementation (G1=15%, G2=45%); concentrations of IL-6, IL-8, and IL-10; and side effects (nausea, vomiting, dizziness, and pruritus). 30666152 2019
Entrez Id: 5053
Gene Symbol: PAH
PAH
0.110 Biomarker phenotype BEFREE The lack of nausea and vomiting during the first trimester suggests that the occurrence of CHD in babies born to women with PKU may be reduced with BH4. 16338627 2005
Entrez Id: 5053
Gene Symbol: PAH
PAH
0.110 Biomarker phenotype HPO
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.110 Biomarker phenotype HPO
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.100 Biomarker phenotype BEFREE However, the additional of a neurokinin-1 receptor antagonist to the standard antiemetic therapy prevents carboplatin-induced nausea and vomiting. 28365889 2017
Entrez Id: 112476
Gene Symbol: PRRT2
PRRT2
0.100 Biomarker phenotype HPO
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.100 Biomarker phenotype HPO
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.100 Biomarker phenotype BEFREE Neurokinin-1 receptor antagonists: review of their role for the prevention of chemotherapy-induced nausea and vomiting in adults. 31194593 2019
Entrez Id: 2717
Gene Symbol: GLA
GLA
0.100 Biomarker phenotype HPO
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.100 Biomarker phenotype BEFREE Rolapitant is a neurokinin-1 receptor antagonist that is approved in combination with other antiemetic agents in adults for the prevention of delayed nausea and vomiting (CINV) associated with initial and repeat courses of emetogenic cancer chemotherapy, including but not limited to highly emetogenic chemotherapy. 30032410 2019
Entrez Id: 4540
Gene Symbol: ND5
ND5
0.100 Biomarker phenotype HPO
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.100 Biomarker phenotype HPO
Entrez Id: 29110
Gene Symbol: TBK1
TBK1
0.100 Biomarker phenotype HPO
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.100 Biomarker phenotype BEFREE Evolving role of neurokinin 1-receptor antagonists for chemotherapy-induced nausea and vomiting. 30323622 2018
Entrez Id: 7461
Gene Symbol: CLIP2
CLIP2
0.100 Biomarker phenotype HPO
Entrez Id: 4750
Gene Symbol: NEK1
NEK1
0.100 Biomarker phenotype HPO